Documents / FOIA release

Quarterly Report-- July 1- September 30, 1953.

Central Intelligence Agency · 1953-10-01 · 24 pages · text by GLM-OCR

This declassified quarterly report covers July 1 to September 30, 1953. It comes from the NIMH Addiction Research Center at the PHS Hospital in Lexington, Kentucky, and was signed by Director of Research Harris Isbell. It describes clinical, biochemical, neurophysiological and psychological studies of addiction, including trials of codeine substitutes, morphine and Nalline mixtures, meperidine addiction, and chronic LSD-25 intoxication, which produced rapid tolerance. It also lists the unit's publications, lectures and film showings. It does not discuss UFOs.

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shadows, dancing dots of light, and spinning circles of color. Frequently, inanimate objects were distorted and changed in size. Occasionally, patients reported seeing visions consisting of rapidly changing fantastic scenes which resembled "Walt Disney Movies." Patients had difficulty in describing these sensations while under the influence of LSD-25 (blocking?) and were much more likely to give good descriptions the day following the experiment. They complained of difficulty in concentration and of a "rush of thoughts." Patients were usually egothetic and somewhat withdrawn during the height of the psychosis. Insight was always maintained.

The effects usually began 30 minutes to one hour after administration of the drug and peak effect was usually reached in one and one-half to three hours; thereafter, effects gradually subsided and were completely dissipated after eight to sixteen hours. Occasionally patients reported "hangovars" tasting for one to several days.

Electroencephalograms were not greatly changed by LSD-25, but synchronization of the electroencephalogram by rhythmic photic stimulation was enhanced. Rhythic stimulation also appeared to enhance perception of colors, patterns, etc., following administration of LSD-25.

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is above. The text was read from the page images by GLM-OCR; expect the odd misread word. 24 pages are in the text index: search them above, or from the library's search.