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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 56.0 -18.0-180.0-

MED50 0.10 -0.032-0.32-

RATIO LD50/MED50 560.0

STATE SOLID

INTRAVENOUS TOXICITY TO MICE

DOSE MG/KG	DILUT ML/KG	REACT. FRACT.	REACTION SIGN	MIN. APPR	DEG-REE	MIN. TO RECOVER
100.0	10.0	2/2	DEATH	74	0
32.0	3.2	2/2	DEC LOCOMOTOR ACTIVITY	124	30	$\cdot$	300
32.0	3.2	1/2	LICKING COMPARTMENT WALLS	825	15 60
32.0	3.2	2/2	SOCIAL INTERACTION ALTERED	132	0 30
32.0	3.2	1/2	INC PREENING	140	60 120
32.0	3.2	1/2	RUBBING NOSE	340	8 30
32.0	3.2	1/2	INC SCRATCHING	440	120 240
32.0	3.2	2/2	EYELID PTOSIS=NONPARALYTIC	149	30	***	300
32.0	3.2	2/2	INC RESPIRATORY DEPTH	161	0 8
32.0	3.2	2/2	DEC RESPIRATORY DEPTH	261	8 30
32.0	3.2	2/2	IRREGULAR RESPIRATORY DEPTH361	30 60
32.0	3.2	2/2	DEC RESPIRATORY RATE	262	0 8
32.0	3.2	2/2	INC RESPIRATORY RATE	162	8	$\cdot$	30
32.0	3.2	2/2	IRREGULAR RESPIRATORY RATE	362	30 60
32.0	3.2	2/2	MOT DEF VERTICAL ROD	371	8	$\cdot$	120
32.0	3.2	2/2	MOT DEF ROTA=ROD	771	8	$\cdot$	60
32.0	3.2	1/2	PILOERECTION	72	60 240
32.0	3.2	2/2	RESTLESSNESS	79	60 300
10.0	10.0	2/2	LICKING COMPARTMENT WALLS	825	30 120

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.