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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 180.0 -56.0-560.0-

MED50 18.0 -5.6=56.0=

RATIO LD50/MED50 10.0

STATE SOLID

DOSE MG/KG	DILUT ML/KG	REACT. FRACT.	INTRAVENOUS TOXICITY TO MICE REACTION SIGN	MIN. APPR	DEG= REE	MIN. TO RECOVER
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	0	***	G 300
100.0	10.0	2/2	SOCIAL INTERACTION ALTERED	132	0 G 300
100.0	10.0	2/2	DEC REARING FREQUENCY	632	0 300
100.0	10.0	1/2	EXOPHTHALMOS	46	180 300
100.0	10.0	1/2	MYDRIASIS	154	15	$\cdot$	300
100.0	10.0	2/2	INC RESPIRATORY DEPTH	161	0 G 300
100.0	10.0	2/2	IRREGULAR RESPIRATORY DEPTH361	8 300
100.0	10.0	2/2	LOW CARRIAGE	175	0 240
32.0	3.2	1/2	LYELID PIOSIS=NONPARALYTIC	149	180	$\cdot$	G 300
32.0	3.2	2/2	MYDRIASIS	154	15	**	300
10.0	10.0	2/2	NO EFFECT	73
DIL. 0.5% M.C. SUSP QS C H2O

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.