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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 320.0 -100.0-1.0+3-

MED50 56.0 -18.0-180.0-

RATIO LD50/MED50 6.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	REACT
FRACT	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG=REE	MIN. TO
RECOVER
320.0	32.0	1/2	DEATH	74	0
320.0	32.0	1/2	DEC LOCOMOTOR ACTIVITY	124	0	***	G 300
320.0	32.0	1/2	DEC SENSITIVITY TO PAIN	229	8 120
320.0	32.0	1/2	DEC SENSITIVITY TO SOUND	230	8	***	120
320.0	32.0	1/2	DEC SENSITIVITY TO TOUCH	231	8	***	120
320.0	32.0	1/2	DEC REARING-FREQUENCY	632	0 G 300
320.0	32.0	1/2	LIMP TAIL	333	8 120
320.0	32.0	1/2	DEC MUSCLE TONE=TRUNK	237	8 60
320.0	32.0	1/2	DEC MUSCLE TONE=LIMBS	437	8 60
320.0	32.0	1/2	DEC PREENING	240	0 G 300
320.0	32.0	1/2	LOW POSTURE	241	60 240
320.0	32.0	1/2	PROSTRATION	43	0 60
320.0	32.0	1/2	EYELID PTOSIS=NONPARALYTIC	149	30	***	G 300
320.0	32.0	1/2	PUPILLARY LIGHT REFLEX ABS	152	8 120
320.0	32.0	1/2	MYDRIASIS	154	8	**	120
320.0	32.0	1/2	INC RESPIRATORY DEPTH	161	0 8
320.0	32.0	1/2	DEC RESPIRATORY DEPTH	261	8 30
320.0	32.0	1/2	DEC RESPIRATORY RATE	262	0 8
320.0	32.0	1/2	INC RESPIRATORY RATE	162	8	$\cdot$	30
320.0	32.0	1/2	IRREGULAR RESPIRATORY RATE	362	0 8
320.0	32.0	1/2	MOT DEF HORIZONTAL WIRE	171	0	***	120

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.