Documents / FOIA release

(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

DOSE
KG/KG	DILUT
ML/KG	REACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG-
REE	MIN. TO
RECOVER
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	8	***	300
100.0	10.0	1/2	MYDRIASIS	154	180	$\cdot$	300
100.0	10.0	1/2	INC RESPIRATORY DEPTH	161	8 300
100.0	10.0	1/2	DEC RESPIRATORY RATE	262	8 300
100.0	10.0	2/2	MOT DEF VERTICAL SCREEN	271	30	$\cdot$	300
100.0	10.0	1/2	MOT DEF HORIZONTAL STRIP	471	30	$\cdot$	300
100.0	10.0	2/2	MOT DEF VERTICAL ROD	371	30	***	300
100.0	10.0	2/2	MOT DEF ROTA=ROD	771	30	$\cdot$	300
100.0	10.0	2/2	MOT DEF INCLINED STRIP	671	30	***	300
32.0	3.2	2/2	DEC LOCOMOTOR ACTIVITY	124	60	$\cdot$	180
10.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	60	$\cdot$	240
3.2	3.2	2/2	NO EFFECT	73
DIL. 0.3H M.C. SUSP QS C 420

LD50 180.0 =56.0=560.0=

MED50 5.6 =1.8=18.0=

RATIO LD50/MED50 32.0

Not linked to a story yet.

About this file

FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.