Documents / FOIA release
This declassified quarterly report covers July 1 to September 30, 1953. It comes from the NIMH Addiction Research Center at the PHS Hospital in Lexington, Kentucky, and was signed by Director of Research Harris Isbell. It describes clinical, biochemical, neurophysiological and psychological studies of addiction, including trials of codeine substitutes, morphine and Nalline mixtures, meperidine addiction, and chronic LSD-25 intoxication, which produced rapid tolerance. It also lists the unit's publications, lectures and film showings. It does not discuss UFOs.
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receiving large amounts of meperidine, were apparent in all 6 cases. One patient who was receiving 300 mg. of meperidine every three hours had a convulsion. Practically all patients exhibited involuntary jerking and twitching of muscle groups. Abstinence could not be precipitated with Nalline in any of these patients. Studies on meperidine addiction are described in the Neurophysiological Section. d. Chronic Intoxication with the Diethylamide of Lysargic Acid (LSD-251). This drug is a semi-synthetic member of the ergot series which produces a toxic psychosis in doses of only 20 to 60 micrograms. The effects of single doses of the drug have been extensively studied both in the United States and Europe, using both psychotic and nonpsychotic patients. Many psychiatrists have described the mental effects produced by the drug as resembling those seen in schizophrenia and some have gone so far as to call LSD-produced psychosis "experimental schizophrenia." No human experimentation on chronic intoxication with this interesting compound has been carried out. It was, therefore, felt that the study of chronic intoxication with the compound was extremely important.
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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is above. The text was read from the page images by GLM-OCR; expect the odd misread word. 24 pages are in the text index: search them above, or from the library's search.