Documents / FOIA release
This declassified quarterly report covers July 1 to September 30, 1953. It comes from the NIMH Addiction Research Center at the PHS Hospital in Lexington, Kentucky, and was signed by Director of Research Harris Isbell. It describes clinical, biochemical, neurophysiological and psychological studies of addiction, including trials of codeine substitutes, morphine and Nalline mixtures, meperidine addiction, and chronic LSD-25 intoxication, which produced rapid tolerance. It also lists the unit's publications, lectures and film showings. It does not discuss UFOs.
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given every 7 to 10 hours in the following order: 3, 10, 6, 11, 4, 5, 14, 12 and 11 mg./kg. It was found that the administration of morphine markedly affected the degree of inhibition of bar pressing. As the dose of morphine was increased the rate of bar pressing during the sounding of the buzzer tended to approach the control rate. An almost linear dose-effect was obtained between 5 and 10 mg.kg. of morphine. The data obtained are consistent with the hypothesis previously developed in human studies; morphine relieves pain by reducing anticipator anxiety caused by painful stimuli. Following further improvement in our apparatus, we intend to study the effects of other drugs, such as pentobarbital, amphetamine, aspirin, etc., and to study the effects of morphine on extinction. b. Effects of Diethylamide of Lysergic Acid on Psychological Tests. Six subjects have been tested before and after the administration of LSD-25. Tests used have been the Korschach, Weschler Gellevue, Goldstein-Scheerer and the Minnesota Multiphasic Personality Inventory. Although the records have not been completely analyzed, the following trends are being observed: performance on those sub-tests of the Korschach-Gellevue scale which requires sustained concentration and attention is consistently lower after LSD-25. The Goldstein-Scheerer test shows no measurable impairment of abstract thinking ability. No systematic changes have been seen in the Korschach 4-98 Declassified by 187475 date FEB 1977.
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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is above. The text was read from the page images by GLM-OCR; expect the odd misread word. 24 pages are in the text index: search them above, or from the library's search.