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Defense Intelligence Reference Document Biosensors And A Survey Of The Present Field

Defense Intelligence Agency · 45 pages · text from the file's own layer

This Defense Intelligence Agency reference document, dated 31 March 2010 (DIA-08-1003-020), was one of a series of advanced technology reports produced in FY 2009 under the Advanced Aerospace Weapon System Applications (AAWSA) program. It surveys biosensors and BioMEMS, covering brain-implanted neuroelectrodes, drug-delivery pumps, implantable glucose sensors, brain-machine interfaces, retinal prostheses, microfluidic lab chips, NASA cell culture systems, and microcantilever sensors. It concludes that the field is expanding rapidly toward nanomechanical systems.

  • p. 7 …developed by the faculty of Biomedical Engineering at Arizona State University. 1 UNCLASSIFIED/ /1"91\ 8ffl81i…
  • p. 8 …Varieties of BioMEMS and Sensors. These BioMEMS devices were made at Arizona State University (ASU). They…
  • p. 9 …subject of research by the present author and by colleagues at Arizona State University. BioMEMS Micromachines…
  • p. 21 …days of use. THERMOPILE IMPLANTABLE GLUCOSE SENSORS Towe et al. at Arizona State University have been…
  • p. 23 …A MEMS Thermopile Glucose Sensor (Towe et al., Arizona State University) Heat energy released in the…
  • p. 37 …Research at Arizona State University has been directed towards overcoming the problems of bulk and need…
  • p. 40 …NASA SPACE APPLICATIONS FOR MICROFLUIDIC SYSTEMS NASA has supported at Arizona State University, the development of…
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red fluorescent protein (RFP) in E. Coli bacterial cells genetically engineered by ASU
microbiologist Dr. Valerie Stout. These bacteria glow when the rec-A gene is active,
indicating a certain type of stress or damage to the bacteria due to the space
environment.
Figure 33. NASA Space Application of Microfluidic Cell Culture System Made by Micromachining (Towe -
ASU research)
Microcantilever MEMs Sensors
The microcantilever is one of the simplest MEMS based biosensor devices, with wide
applications in detection of very small amounts of specific chemicals through a process
known as affinity sensing. This can detect gas composition, antigens in the air, toxic
gases and particulates.
The use of microcantilevers as transducers for chemical and biochemical sensing has
only become widespread in the last few years, mainly due to their use in the
development of microsensor arrays. The idea is quite simple: the surface of the
cantilever, a thin rectangular beam clamped at one end, is chemically modified to react
with specific compounds. The mass deposition that follows the chemical reaction causes
a stress, and this leads to a detectable bending of the cantilever as illustrated in Figure
34.
36
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 45 pages are in the text index: search them above, or from the library's search.