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Defense Intelligence Reference Document Biosensors And A Survey Of The Present Field

Defense Intelligence Agency · 45 pages · text from the file's own layer

This Defense Intelligence Agency reference document, dated 31 March 2010 (DIA-08-1003-020), was one of a series of advanced technology reports produced in FY 2009 under the Advanced Aerospace Weapon System Applications (AAWSA) program. It surveys biosensors and BioMEMS, covering brain-implanted neuroelectrodes, drug-delivery pumps, implantable glucose sensors, brain-machine interfaces, retinal prostheses, microfluidic lab chips, NASA cell culture systems, and microcantilever sensors. It concludes that the field is expanding rapidly toward nanomechanical systems.

  • p. 7 …developed by the faculty of Biomedical Engineering at Arizona State University. 1 UNCLASSIFIED/ /1"91\ 8ffl81i…
  • p. 8 …Varieties of BioMEMS and Sensors. These BioMEMS devices were made at Arizona State University (ASU). They…
  • p. 9 …subject of research by the present author and by colleagues at Arizona State University. BioMEMS Micromachines…
  • p. 21 …days of use. THERMOPILE IMPLANTABLE GLUCOSE SENSORS Towe et al. at Arizona State University have been…
  • p. 23 …A MEMS Thermopile Glucose Sensor (Towe et al., Arizona State University) Heat energy released in the…
  • p. 37 …Research at Arizona State University has been directed towards overcoming the problems of bulk and need…
  • p. 40 …NASA SPACE APPLICATIONS FOR MICROFLUIDIC SYSTEMS NASA has supported at Arizona State University, the development of…
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Figure 23. A MEMS Microelectrode Array Implanted Into the Cortex of a Rat Brain. The lead wires from the
device can be seen. (NeuroNexus Inc.)
RETINAL DEVICES USING BIOMEMS
An example of MEMS being used in conjunction with wireless implantable systems is the
retinal implant.
These devices attempt to augment vision where it has failed due to problems such as
macular degeneration and retinitis pigmentosa. The basic idea is to use a miniature
video camera and connect it to an electrode array in the eye such that the scene in
view is converted to electrical impulses used to stimulate the sensation of sight by
direct stimulation of the receptors in the eye. Figure 24 shows this idea.
Figure 25 shows a microelectrode array that has been manufactured on a polymer
substrate such that it is exceedingly thin and flexible. The flexibility is needed so that it
conforms to the curved shape of the back of the eye. The electrode pads seen are
attached by a flexible cable.
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Report, from the dia collection. The PDF is mirrored here; the original link is under it. 45 pages are in the text index: search them above, or from the library's search.