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Defense Intelligence Reference Document Biosensors And A Survey Of The Present Field

Defense Intelligence Agency · 45 pages · text from the file's own layer

This Defense Intelligence Agency reference document, dated 31 March 2010 (DIA-08-1003-020), was one of a series of advanced technology reports produced in FY 2009 under the Advanced Aerospace Weapon System Applications (AAWSA) program. It surveys biosensors and BioMEMS, covering brain-implanted neuroelectrodes, drug-delivery pumps, implantable glucose sensors, brain-machine interfaces, retinal prostheses, microfluidic lab chips, NASA cell culture systems, and microcantilever sensors. It concludes that the field is expanding rapidly toward nanomechanical systems.

  • p. 2 …a series of advanced technology reports produced in FY 2009 under the Defense Intelligence Agency, J…
  • p. 6 …This paper examines some of the most recent advances in the field, as well as the…
  • p. 7 …Advanced systems can perform several tests on the sample at one time. There are also drug…
  • p. 10 …This is the idea behind advanced devices that allow quadriplegics to interact with their environment. Signals…
  • p. 14 …There has been the application of MEMS technologies in the creation of better ways to deliver…
  • p. 19 …The human body is an exceptionally hostile environment for foreign materials. Even our most advanced biosensors…
  • p. 21 …sensor using this kind of approach (Advanced Biosensors Inc). The fine needle geometry is generally meant…
  • p. 45 …The economic driving forces for this miniaturization are strong for health care and biology. Advanced fabrication…
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Figure 23. A MEMS Microelectrode Array Implanted Into the Cortex of a Rat Brain. The lead wires from the
device can be seen. (NeuroNexus Inc.)
RETINAL DEVICES USING BIOMEMS
An example of MEMS being used in conjunction with wireless implantable systems is the
retinal implant.
These devices attempt to augment vision where it has failed due to problems such as
macular degeneration and retinitis pigmentosa. The basic idea is to use a miniature
video camera and connect it to an electrode array in the eye such that the scene in
view is converted to electrical impulses used to stimulate the sensation of sight by
direct stimulation of the receptors in the eye. Figure 24 shows this idea.
Figure 25 shows a microelectrode array that has been manufactured on a polymer
substrate such that it is exceedingly thin and flexible. The flexibility is needed so that it
conforms to the curved shape of the back of the eye. The electrode pads seen are
attached by a flexible cable.
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Report, from the dia collection. The PDF is mirrored here; the original link is above. 45 pages are in the text index: search them above, or from the library's search.