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Defense Intelligence Reference Document Biosensors And A Survey Of The Present Field

Defense Intelligence Agency · 45 pages · text from the file's own layer

This Defense Intelligence Agency reference document, dated 31 March 2010 (DIA-08-1003-020), was one of a series of advanced technology reports produced in FY 2009 under the Advanced Aerospace Weapon System Applications (AAWSA) program. It surveys biosensors and BioMEMS, covering brain-implanted neuroelectrodes, drug-delivery pumps, implantable glucose sensors, brain-machine interfaces, retinal prostheses, microfluidic lab chips, NASA cell culture systems, and microcantilever sensors. It concludes that the field is expanding rapidly toward nanomechanical systems.

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POLYMER BIOMEMS ELECTRODES
Polymer materials like polyimide are widely used for neuroprostheses because they are
inert, flexible and metal films adhere well to them.
Manufacturing of neural electrodes can be achieved by metal vacuum deposition
through photolithographic masks and by a process of RF ablation or etching. Figure 22
shows some products of NeuroNexus Inc that result from this process. These electrodes
are batch fabricated and have a high reproducibility of geometrical shape, electrical
properties, and mechanical properties.
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Figure 22. Polymer-Based Cortical Penetrating Neuroelectrodes Made by Processes of Thin Film
Deposition and RF Etching (Neuronexus Inc)
They also have the advantage of small size, resulting in minimal displacement of the
neural tissue and their long leg lengths give a high spatial resolution at various depths
up to 1 cm. The multiple parallel shanks, provide horizontal spatial sampling and
independent recording/stimulation among sites.
Figure 23 shows one of these devices introduced into the cortex of an exposed rat
brain.
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Report, from the dia collection. The PDF is mirrored here; the original link is above. 45 pages are in the text index: search them above, or from the library's search.