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This Defense Intelligence Agency reference document, dated 7 January 2010 and prepared under the Acquisition Threat Support series, surveys biomaterials used in medicine. It covers biocompatibility, biosensor membranes, silicones, Teflon, biodegradable polymers, hydrogels, titanium, bioceramics, tissue constructs, cardiovascular stents, contact lenses, drug delivery and dialysis. It concludes that biomaterial performance underlies many medical devices, that the industry is slow to adopt new materials because of testing costs, and that innovation mainly involves new applications of established materials.
UNCLASSIFIED/11P8fl 8FFIIJll1L WEE SHIia¥ Medical Devices Used in the Bloodstream Blood contact time Catheters Guidewires Sensors Pacemaker Vascular Graft Heart Valve Stent Extracorporeal Oxygenation Artificial Kidney (hemodialyzer) Total Artificial Heart Left Ventricular Assist Device (LVAD) Min-days Min-hrs Min-months 10yrs lifetime lifetime lifetime hrs hrs 10 yrs Days-yrs Figure 2i.. Some of the More Popular Blomedlcal Devices and Duration of Their Blood Contact Biomaterials. are''used as vascular grafts for art~~Y replacements in.which they are .. _ connected (grafted). onto natural blood vessels at both ends. When arteries, particularly the coronary arteries and the vessels of the lower limbs, become blocked by fatty deposits (atherosclerosis), segments in some cases can be replaced with grafts. Figure 22 shows commercial vascular grafts made by Gore Medical (Flagstaff, Arizona, USA). Figure 22. Gore Medical Teflon Foam Used In Vascular Grafts. These are artificial blood vessels used to replace blood vessels In the human body damaged by accident, atherothrosclerosls, or diabetic vascular disease. 16 .UNCLASSIFIED/,1P91l 9PPl81f1k WO& 811Jb¥
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Report, from the dia collection. The PDF is mirrored here; the original link is above. 32 pages are in the text index: search them above, or from the library's search.