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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

  • p. 92 …DEG= MIR MG/KG ML/KG FRACT. REACTION SIGN APPR REE REC 0.32 16.0…
INTRAVENOUS TOXICITY TO MICE

DOSE MG/KG	DILUT ML/KG	REACT. FRACT.	INTRAVENOUS TOXICITY TO MICE REACTION SIGN	MIN. APPR	DEG-REE	MIN. TO RECOVERY
0.80	40.0	2/2	DEC LOCOMOTOR ACTIVITY 124	8	***	G 30
0.80	40.0	2/2	DEC PREENING 240	8 G 30
0.80	40.0	1/2	EYELID PIOSIS-NONPARALYTIC 149	30	***	G 30
0.80	40.0	2/2	PUPILLARY LIGHT REFLEX ABS 152	8 12
0.80	40.0	2/2	MYDRIASIS 154	8	**	12
0.80	40.0	2/2	DEC RESPIRATORY DEPTH 261	0
0.80	40.0	2/2	INC RESPIRATORY DEPTH 161	8 G 30
0.80	40.0	2/2	IRREGULAR RESPIRATORY DEPTH361	0 G 30
0.80	40.0	2/2	INC RESPIRATORY RATE 162	0	$\cdot$
0.80	40.0	2/2	DEC RESPIRATORY RATE 262	8 G 30
0.80	40.0	2/2	IRREGULAR RESPIRATORY RATE 362	0 30
0.80	40.0	1/2	MOT DEF HORIZONTAL STRIP 471	8	$\cdot$	3
0.80	40.0	1/2	MOT DEF VERTICAL ROD 371	8	$\cdot$	3
0.80	40.0	2/2	MOT DEF INCLINED STRIP 671	8	$\cdot$	3
0.32	16.0	1/2	DEC LOCOMOTOR ACTIVITY 124	30	$\cdot$	12
0.32	16.0	2/2	INC SENSITIVITY TO SOUND 130	15	***	18
0.32	16.0	2/2	INC SENSITIVITY TO TOUCH 131	15	$\cdot$	18
0.32	16.0	2/2	STRAUB TAIL 233	8 3
0.32	16.0	1/2	INC PREENING 140	8 3
0.32	16.0	2/2	IRREGULAR RESPIRATORY DEPTH361	0 12

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.