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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

  • p. 92 …DEG= MIR MG/KG ML/KG FRACT. REACTION SIGN APPR REE REC 0.32 16.0…
INTRAVENOUS TOXICITY TO MICE

DOSE	DILUT	REACT.	REACTION SIGN	MIN.	DEG-	MIN. TO
MG/KG	ML/KG	FRACT.
0.80	40.0	2/2	MYDRIASIS	154	8	**	180
0.80	40.0	2/2	DEC LOCOMOTOR ACTIVITY	124	15	***	120
0.80	40.0	2/2	INC SENSITIVITY TO SOUND	130	15	$\cdot$	180
0.80	40.0	2/2	INC SENSITIVITY TO TOUCH	131	15	***	180
0.80	40.0	2/2	SOCIAL INTERACTION ALTERED	132	0 180
0.80	40.0	2/2	DEC REARING FREQUENCY	632	0 120
0.80	40.0	2/2	PUPILLARY LIGHT REFLEX ABS	152	8 180
0.80	40.0	1/2	INC RESPIRATORY DEPTH	161	15 60
0.80	40.0	1/2	IRREGULAR RESPIRATORY DEPTH	361	0 15
0.80	40.0	1/2	DEC RESPIRATORY RATE	262	15 60
0.80	40.0	1/2	IRREGULAR RESPIRATORY RATE	362	0 15
0.32	16.0	1/2	INC SENSITIVITY TO SOUND	130	8	***	120
0.32	16.0	1/2	INC SENSITIVITY TO TOUCH	131	30	$\cdot$	120
0.32	16.0	1/2	PUPILLARY LIGHT REFLEX ABS	152	8 180
0.32	16.0	1/2	MYDRIASIS	154	8	**	180
0.10	5.0	1/2	INC REARING FREQUENCY	432	8 15
0.10	5.0	1/2	PUPILLARY LIGHT REFLEX ABS	152	8 120
0.10	5.0	1/2	MYDRIASIS	154	8	**	120

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.