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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

  • p. 92 …DEG= MIR MG/KG ML/KG FRACT. REACTION SIGN APPR REE REC 0.32 16.0…
LD50 180.0 -56.0-550.0-

MED50 3.2 -1.0-10.0-

RATIO LD50/MED50 56.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	REACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG=
REE	MIN. TO
RECOVER
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	1/2	INC LOCOMOTOR ACTIVITY	224	0	$\cdot$	1
100.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	0	***	100
100.0	10.0	1/2	CIRCLING MOVEMENTS	025	0 2
100.0	10.0	2/2	DEC SENSITIVITY TO PAIN	229	8 40
100.0	10.0	2/2	DEC SENSITIVITY TO SOUND	230	0	$\cdot$	300
100.0	10.0	2/2	DEC SENSITIVITY TO TOUCH	231	8	$\cdot$	180
100.0	10.0	2/2	PINNAL REFLEX DEPR	331	8	$\cdot$	120
100.0	10.0	2/2	SOCIAL INTERACTION ALTERED	132	0 120
100.0	10.0	2/2	DEC REARING FREQUENCY	632	0 160
100.0	10.0	1/2	STRAUB TAIL	233	0 9
100.0	10.0	1/2	LIMP TAIL	333	0 30
100.0	10.0	1/2	ATAXIA	35	0	***	15
100.0	10.0	2/2	DEC PREENING	240	0 140
100.0	10.0	1/2	LOW POSTURE	241	0 60
100.0	10.0	1/2	EXTENSION OF LIMBS	341	0 30
100.0	10.0	1/2	RIGHTING REFLEX DEPR	742	0 6
100.0	10.0	2/2	EYELID PTOSIS-NONPARALYTIC	149	60	***	240
100.0	10.0	2/2	PUPILLARY LIGHT REFLEX ABS	152	8 120
100.0	10.0	2/2	MYDRIASIS	154	8	$\cdot$	120

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.