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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 56.0 -18.0-180.0-

MED50 1.8 =0.55=5.6=

RATIO LD50/MED50 31.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	REACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG-
REE	MIN. TO
RECOVER
100.0	10.0	2/2	DEATH	74	0
32.0	3.2	2/2	DEC LOCOMOTOR ACTIVITY	124	0	***	G 300
32.0	3.2	1/2	ABNORMAL REACTION TO PAIN	429	30 G 330
32.0	3.2	2/2	DEC SENSITIVITY TO SOUND	230	15	$\cdot$	G 300
32.0	3.2	2/2	DEC SENSITIVITY TO TOUCH	231	30	$\cdot$	G 300
32.0	3.2	2/2	SOCIAL INTERACTION ALTERED	132	0 180
32.0	3.2	2/2	DEC REARING FREQUENCY	632	0 G 300
32.0	3.2	2/2	DEC PREENING	240	0 G 300
32.0	3.2	2/2	EYELID PTOSIS=NONPARALYTIC	149	30	***	G 300
32.0	3.2	1/2	LACRIMATION	50	240	$\cdot$	G 300
32.0	3.2	2/2	PUPILLARY LIGHT REFLEX ABS	152	8 30
32.0	3.2	2/2	MYDRIASIS	154	8	**	30
32.0	3.2	2/2	DYSPNEA	60	8	-$\cdot$	300
32.0	3.2	2/2	INC RESPIRATORY DEPTH	161	0 G 300
32.0	3.2	2/2	DEC RESPIRATORY RATE	262	0 G 300
32.0	3.2	1/2	IRREGULAR RESPIRATORY RATE	362	240 G 300
32.0	3.2	2/2	DECREASED TEMPERATURE	267	30 G 300
32.0	3.2	1/2	MOT DEF HORIZONTAL WIRE	171	30	$\cdot$	G 300
32.0	3.2	2/2	MOT DEF HORIZONTAL STRIP	471	8	***	G 300
32.0	3.2	2/2	MOT DEF VERTICAL ROD	371	30	$\cdot$	G 300

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.