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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 56.00 -10.00-320.00-

MED50 10.0 -3.2-32.0=

RATIO LD50/MED50 5.6

STATE SOLID

INTRAVENOUS TOXICITY TO NICE

DOSE
MG/KG	DILUT
ML/KG	REACT
FRACT	REACTION SIGN	MIN.
APPR	DEG-
REE	MIN. TO
RECOVER
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	1/2	DEATH	74	0
100.0	10.0	1/2	DEC LOCOMOTOR ACTIVITY	124	0	***
100.0	10.0	1/2	DEC SENSITIVITY TO PAIN	229	15
100.0	10.0	1/2	DEC SENSITIVITY TO TOUCH	231	30	$\cdot$
100.0	10.0	1/2	DEC REARING FREQUENCY	632	0	$\cdot$
100.0	10.0	1/2	EYELID PTOSIS=NONPARALYTIC	149	120	***
100.0	10.0	1/2	MYDRIASIS	154	60	$\cdot$
100.0	10.0	1/2	INC RESPIRATORY DEPTH	151	0	$\cdot$
100.0	10.0	1/2	IRREGULAR RESPIRATORY DEPTH351	8 $\cdot$
100.0	10.0	1/2	DEC RESPIRATORY RATE	262	0	$\cdot$
100.0	10.0	1/2	MOT DEF HORIZONTAL STRIP	471	30	$\cdot$
100.0	10.0	1/2	MOT DEF VERTICAL ROD	371	30	***
100.0	10.0	1/2	MOT DEF ROYA=ROD	771	30	***
100.0	10.0	1/2	MOT DEF INCLINED STRIP	671	30	$\cdot$
100.0	10.0	1/2	LOW CARRIAGE	175	0
32.0	3.2	1/2	DEATH	74	0
31.0	3.2	1/2	DEC LOCOMOTOR ACTIVITY	124	8	$\cdot$
32.0	3.2	1/2	DEC SENSITIVITY TO TOUCH	231	30	$\cdot$

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.