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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 180.0 -140.0-220.0-

MED50 0.56 -0.18-1.8-

RATIO LD50/MED50 320.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	REACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG-
REE	MIN. TO
RECOVER
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	2/2	INC LOCOMOTOR ACTIVITY	224	0	***	15
100.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	15	***	300
100.0	10.0	2/2	CIRCLING MOVEMENTS	025	0 15
100.0	10.0	2/2	SOCIAL INTERACTION ALTERED	132	0 G 300
100.0	10.0	2/2	DEC REARING FREQUENCY	632	0 120
100.0	10.0	2/2	ATAXIA	35	0	$\cdot$	15
100.0	10.0	2/2	DEC PREENING	240	0 30
100.0	10.0	2/2	GRASPING REFLEX ABS	642	0 30
100.0	10.0	1/2	MYDRIASIS	154	0	***	240
100.0	10.0	2/2	INC RESPIRATORY RATE	162	0	$\cdot$	300
100.0	10.0	1/2	MOT DEF HORIZONTAL WIRE	171	0	***	180
100.0	10.0	1/2	MOT DEF VERTICAL SCREEN	271	0	***	180
100.0	10.0	2/2	MOT DEF HORIZONTAL STRIP	471	0	***	240
100.0	10.0	2/2	MOT DEF VERTICAL ROD	371	0	***	140
100.0	10.0	2/2	MOT DEF ROTA=ROD	771	0	***	240
100.0	10.0	2/2	MOT DEF INCLINED STRIP	671	0	***	240
100.0	10.0	1/2	PILOERECTION	72	120 240
32.0	3.2	2/2	INC LOCOMOTOR ACTIVITY	224	0	***	120

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.