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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 11.0 -8.9-14.0-

MED50 0.56 -0.18=1.8-

RATIO LD50/MED50 20.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	REACT.
FRACT.	REACTION SIGN MIN.
APPR	DEG=REE	MIN. TO
RECOVER
32.0	3.2	2/2	DEATH	74	0
10.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	0	***	180
10.0	10.0	2/2	SOCIAL INTERACTION ALTERED	132	0 240
10.0	10.0	2/2	DEC REARING FREQUENCY	632	0 240
10.0	10.0	1/2	STRAUB TAIL	233	8 30
10.0	10.0	1/2	SUB-CONVULSIVE MOVEMENTS	436	8 15
10.0	10.0	2/2	OPISTHOTONOS	38	0 30
10.0	10.0	2/2	DEC PREENING	240	0 180
10.0	10.0	1/2	EXTENSION OF LIMBS	341	8 50
10.0	10.0	2/2	UNUSUAL POSTURE	541	0 15
10.0	10.0	1/2	LABYRINTHINE REFLEX DEPR	942	8 30
10.0	10.0	2/2	TREMCRS=REST AND MOVEMENT	144	8	$\cdot$	30
10.0	10.0	2/2	PUPILLARY LIGHT REFLEX ABS	152	8 60
10.0	10.0	2/2	MYDRIASIS	154	8	$\cdot$	60
10.0	10.0	2/2	INC RESPIRATORY DEPTH	161	0 120
10.0	10.0	2/2	IRREGULAR RESPIRATORY DEPTH361	0 30
10.0	10.0	2/2	IRREGULAR RESPIRATORY RATE	362	0 60
10.0	10.0	2/2	MOT DEF HORIZONTAL WIRE	171	0	***	30
10.0	10.0	2/2	MOT DEF VERTICAL SCREEN	271	0	***	30
10.0	10.0	2/2	MOT DEF HORIZONTAL STRIP	471	0	***	120

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.