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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 36.0 -26.0=49.0=

MED50 0.56 -0.18-1.8-

RATIO LD50/MED50 63.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	RFACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG-
REE	MIN.
RECO
100.0	10.0	2/2	DEATH	74	0
32.0	3.2	1/2	DEATH	74	0
32.0	3.2	1/2	INC LOCOMOTOR ACTIVITY	224	0	***
32.0	3.2	1/2	DEC LOCOMOTOR ACTIVITY	124	15	***
32.0	3.2	1/2	INC PHONATION	128	15
32.0	3.2	1/2	DEC SENSITIVITY TO PAIN	229	15
32.0	3.2	1/2	INC REACTIVITY TO SOUND	330	0	***	G
32.0	3.2	1/2	INC SENSITIVITY TO TOUCH	131	15	$\cdot$
32.0	3.2	1/2	HEAD TWITCH	531	0	$\cdot$
32.0	3.2	1/2	DEC REARING HEIGHT	732	0
32.0	3.2	1/2	STRAUB TAIL	233	0
32.0	3.2	1/2	ATAXIA	35	0	***
32.0	3.2	1/2	CLONIC CONVULSIONS	136	0
32.0	3.2	1/2	DEC PREENING	240	0
32.0	3.2	1/2	EXTENSION OF LIMBS	341	0
32.0	3.2	1/2	MYDRIASIS	154	0	***. G
32.0	3.2	1/2	INC RESPIRATORY RATE	162	0	$\cdot$
32.0	3.2	1/2	MOT DEF HORIZONTAL WIRE	171	0	***
32.0	3.2	1/2	MOT DEF VERTICAL SCREEN	271	0	***
32.0	3.2	1/2	MOT DEF HORIZONTAL STRIP	471	0	***

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.