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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

LD50 180.0 -56.0-560.0-

MED50 0.56 -0.18-1.8-

STATE SOLID

RATIO LD50/MED50 320.0

DOSE MG/KG	DILUT ML/KG	REACT. FRACT.	INTRAVENOUS TOXICITY TO MICE REACTION SIGN	MIN. APPR	DEG-REE	MIN. REC.
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	2/2	DEC LOCONOTOR ACTIVITY	124	8	***
100.0	10.0	2/2	DEC SENSITIVITY TO PAIN	229	8
100.0	10.0	2/2	DEC SENSITIVITY TO TOUCH	231	8	$\cdot$
100.0	10.0	2/2	PINNAL REFLEX ABS	431	8	***
100.0	10.0	2/2	SOCIAL INTERACTION ALTERED	132	0 G
100.0	10.0	2/2	DEC REARING FREQUENCY	632	0 G
100.0	10.0	2/2	STRAUB TAIL	233	0
100.0	10.0	1/2	CLONIC CONVULSIONS	136	0
100.0	10.0	1/2	TONIC CONVULSIONS	236	0
100.0	10.0	2/2	CPI5THOTONOS	38	0
100.0	10.0	2/2	DEC PREENING	240	0
100.0	10.0	2/2	LOW POSTURE	241	0
100.0	10.0	2/2	RIGHTING REFLEX ABS	842	0
100.0	10.0	2/2	LABYRINTHINE REFLEX DEPR	942	0
100.0	10.0	2/2	EYELID PTOSIS-NONPARALYTIC	149	15	$\cdot$
100.0	10.0	2/2	PUPILLARY LIGHT REFLEX ABS	152	0
100.0	10.0	4/4	MYDRIASIS	154	0	**
100.0	10.0	2/2	INC RESPIRATORY DEPTH	161	0
100.0	10.0	2/2	DEC RESPIRATORY RATE	262	0

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is under it. The text was read from the page images by an OCR model; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.