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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by GLM-OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

Read from the scan by GLM-OCR; expect the odd misread word.

LD50 130.0 -100.0-160.0=

MED50 5,6 =1,8=18,0=

RATIO LD50/MED50 22.0

STATE SOLID

DOSE
MG/KG	DILUT
ML/KG	REACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG-
REE	MIN. TO
RECOVER
100.0	10.0	2/2	DEC LOCOMOTOR ACTIVITY	124	8	***	G 300
100.0	10.0	2/2	DEC SENSITIVITY TO PAIN	229	60 180
100.0	10.0	2/2	DEC SENSITIVITY TO SOUND	230	60	$\cdot$	190
100.0	10.0	2/2	SOCIAL INTERACTION ALTERED	132	0 G 300
100.0	10.0	2/2	DEC REARING FREQUENCY	532	0 G 300
100.0	10.0	2/2	DEC PREENING	240	0 G 300
100.0	10.0	2/2	LOW POSTURE	241	30 180
100.0	10.0	2/2	EYELID PYOSIS-NONPARALYTIC	149	60	***	G 300
100.0	10.0	2/2	PUPILLARY LIGHT REFLEX.ABS	152	30 240
100.0	10.0	2/2	MYDRIASIS	154	30	**	240
100.0	10.0	2/2	INC RESPIRATORY DEPTH	161	0 240
100.0	10.0	2/2	IRREGULAR RESPIRATORY DEPTH361	0 120
100.0	10.0	2/2	DEC RESPIRATORY RATE	262	0 240
100.0	10.0	2/2	IRREGULAR RESPIRATORY RATE	362	0 120
100.0	10.0	1/2	MOT DEF HORIZONTAL WIRE	171	0	$\cdot$	15
100.0	10.0	2/2	MOT DEF VERTICAL SCREEN	271	8	$\cdot$	30
100.0	10.0	2/2	MOT DEF HORIZONTAL STRIP	471	8	***	150
100.0	10.0	2/2	MOT DEF VERTICAL ROD	371	0	$\cdot$	120
100.0	10.0	2/2	MOT DEF ROTA-ROD	771	0	***	120
100.0	10.0	2/2	MOT DEF INCLINED STRIP	671	0	***	150
100.0	10.0	2/2	LOW CARRIAGE	175	0 110

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is above. The text was read from the page images by GLM-OCR; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.