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(Estimated Pub Date) Volume 2 Re Intravenous Toxicity to Mice Reaction Sign; Physical and Neurological Examination of Cats; and Other Statistical Reports. (Projects Unknown; Undated)

Central Intelligence Agency · 1966-01-01 · 438 pages · text by GLM-OCR

This undated Central Intelligence Agency release, catalogued with an estimated date of 1966, is Volume 2 of a set of pharmacological test data on compounds identified only by number, from unknown projects. It holds tables on intravenous toxicity in mice, giving LD50 and MED50 values and reaction signs. It also has tables on the dominance behavior of squirrel monkeys and on blood pressure, heart rate and respiration in chloralosed cats. The text contains no conclusions and does not mention aerial phenomena.

Read from the scan by GLM-OCR; expect the odd misread word.

LD50 130.0 ~100.0=150.0=

MED50 0.55 -0.13-1.3-

RATIO LD50/MED50 220.0

INTRAVENOUS TOXICITY TO MICE

DOSE
MG/KG	OILUT
ML/KG	REACT.
FRACT.	INTRAVENOUS TOXICITY TO MICE
REACTION SIGN	MIN.
APPR	DEG.
REE	MIN. TO
RECOVER
320.0	32.0	2/2	DEATH	74	0
100.0	10.0	1/2	DEATH	74	0
100.0	10.0	1/2	DEC LOCOMOTOR ACTIVITY	124	0	***	G 300
100.0	10.0	1/2	SOCIAL INTERACTION ALTERED	132	0 G 300
100.0	10.0	1/2	DEC REARING FREQUENCY	632	0 30
100.0	10.0	1/2	ATAXIA	35	0	***	30
100.0	10.0	1/2	CLONIC CONVULSIONS	136	0 15
100.0	10.0	1/2	OPISTHOTONOS	38	0 8
100.0	10.0	1/2	FANNED=FLEXED DIGITS	141	0 8
100.0	10.0	1/2	LOW POSTURE	241	0 8
100.0	10.0	1/2	EXTENSION OF LIMBS	341	0 6
100.0	10.0	1/2	UNUSUAL POSTURE	541	0 8
100.0	10.0	1/2	PLACING REFLEX ABS	442	0 8
100.0	10.0	1/2	GRASPING REFLEX ABS	642	0 15
100.0	10.0	1/2	LABYRINTHINE REFLEX DEPR	942	0 8
100.0	10.0	1/2	TREMORS=REST AND MOVEMENT	144	0 8
100.0	10.0	1/2	RIGHTING REFLEX ABS	842	0 8
100.0	10.0	1/2	MIOSIS	254	30	**	G 300
100.0	10.0	1/2	INC RESPIRATORY RATE	162	0	$\cdot$	G 300
100.0	10.0	1/2	IRREGULAR RESPIRATORY RATE	362	0 30

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is above. The text was read from the page images by GLM-OCR; expect the odd misread word. 438 pages are in the text index: search them above, or from the library's search.