Documents / FOIA release

Quarterly Report-- July 1- September 30, 1953.

Central Intelligence Agency · 1953-10-01 · 24 pages · text by GLM-OCR

This declassified quarterly report covers July 1 to September 30, 1953. It comes from the NIMH Addiction Research Center at the PHS Hospital in Lexington, Kentucky, and was signed by Director of Research Harris Isbell. It describes clinical, biochemical, neurophysiological and psychological studies of addiction, including trials of codeine substitutes, morphine and Nalline mixtures, meperidine addiction, and chronic LSD-25 intoxication, which produced rapid tolerance. It also lists the unit's publications, lectures and film showings. It does not discuss UFOs.

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## A. GENERAL

During the last of June and the first part of July, 1953, the processing of purchase vouchers and of personnel payrolls was transferred from the hospital's administrative division to the National Institute of Mental Health. This administrative change has functioned very well and only minor difficulties have been encountered. Uncertainties with respect to the budget for the current fiscal year have hampered purchasing to some extent. The project being carried on for the Department of Defense was reactivated during the month of July. The project is still concerned with the development of a synthetic substitute for codeine.

Clinical studies during the quarter were largely concerned with continuing search for codeine substitutes, the addiction liability of mixtures of morphine and Naline, addiction to meperidine, with the clinical endocrinology of addiction, and with chronic intoxication of the diethylamide of lysergic acid (LSD-254). Another phase of studies on the clinical endocrinology of addiction was completed during the quarter. It was found that the edrensals and the testes will respond to stimulation by the specific adrenocorticotropic and gonadotropic hormones of the anterior pituitary during maintained morphine

A-66

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FOIA release, from the cia-readingroom collection. The PDF is mirrored here; the original link is above. The text was read from the page images by GLM-OCR; expect the odd misread word. 24 pages are in the text index: search them above, or from the library's search.